CompetitivereversIBLeinhibitorofinterleukin-2(IL-2)bindingtoitsreceptor(IC50=3μMforinhibitionofIL-2interactionwithIL-2Rα-subunit).AppearstocompetewithIL-2RαforitsbindingsiteonIL-2.
M.Wt | 560.57 |
Formula | C26H30N4O3.CF3CO2H |
Storage | Desiccateat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 1217448-66-2 |
PubChemID | 16760522 |
InChIKey | BVMWPONRCOSTMK-RFPXDPOKSA-N |
Smiles | FC(F)(F)C(O)=O.NC(N1CCC[C@H](CC(N[C@H](C(OC)=O)CC2=CC=C(C#CC3=CC=CC=C3)C=C2)=O)C1)=N |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 28.03 | 50 | |
ethanol | 2.8 | 5 |
Thefollowingdataisbasedontheproductmolecularweight560.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.78mL | 8.92mL | 17.84mL |
5mM | 0.36mL | 1.78mL | 3.57mL |
10mM | 0.18mL | 0.89mL | 1.78mL |
50mM | 0.04mL | 0.18mL | 0.36mL |