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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Ro 26-4550 trifluoroacetate/1794/10/10 mg
产品编号:1794/10
市  场 价:¥5380.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$269.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Ro 26-4550 trifluoroacetate/1794/10/10 mg
商品介绍
Description:CompetitiveinhibitorofIL-2/IL-2Rαreceptorinteraction
ChemicalName:N-[[(3R)-1-(Aminoiminomethyl)-3-piperidinyl]acetyl]-4-(phenylethynyl)-L-phenylalaninemethylestertrifluoroacetate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CompetitivereversIBLeinhibitorofinterleukin-2(IL-2)bindingtoitsreceptor(IC50=3μMforinhibitionofIL-2interactionwithIL-2Rα-subunit).AppearstocompetewithIL-2RαforitsbindingsiteonIL-2.

TechnicalData

M.Wt560.57
FormulaC26H30N4O3.CF3CO2H
StorageDesiccateat+4°C
Purity≥98%(HPLC)
CASNumber1217448-66-2
PubChemID16760522
InChIKeyBVMWPONRCOSTMK-RFPXDPOKSA-N
SmilesFC(F)(F)C(O)=O.NC(N1CCC[C@H](CC(N[C@H](C(OC)=O)CC2=CC=C(C#CC3=CC=CC=C3)C=C2)=O)C1)=N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.0350
ethanol2.85

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight560.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.78mL8.92mL17.84mL
5mM0.36mL1.78mL3.57mL
10mM0.18mL0.89mL1.78mL
50mM0.04mL0.18mL0.36mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet