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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Radicicol/1589/1/1 mg
产品编号:1589/1
市  场 价:¥2580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>白蛋白>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Radicicol/1589/1/1 mg
商品介绍
Description:Hsp90inhibitor.Antifungalantibiotic
ChemicalName:(1aR,2Z,4E,14R,15aR)-8-Chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-6H-oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Antifungalantibiotic.Inhibitsheatshockprotein90(Hsp90)activitybybindingtotheATP-bindingpocket,subsequentlysuppressingcelltransformationinducedbysrc,rasandmos.Repressesestrogenreceptortranscriptionalactivityandinhibitsangiogenesis.

TechnicalData

M.Wt364.78
FormulaC18H17ClO6
StorageDesiccateat-20°C
Purity≥98%(HPLC)
CASNumber12772-57-5
PubChemID6323491
InChIKeyWYZWZEOGROVVHK-GTMNPGAYSA-N
SmilesO=C2/C=C/C=C[C@@H](O3)[C@H]3C[C@@H](C)OC(C1=C(O)C=C(O)C(Cl)=C1C2)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
ethanol9.1225

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight364.78.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.74mL13.71mL27.41mL
5mM0.55mL2.74mL5.48mL
10mM0.27mL1.37mL2.74mL
50mM0.05mL0.27mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet