SelectiveinhibitorofLFA-1(lymphocytefunction-associatedantigen-1)adhesiontosolubleintercellularadhesionmolecule(sICAM)(IC50=5μMinHL60cells).
RWJ50271isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 410.41 |
| Formula | C18H17F3N4O2S |
| Storage | StoreatRT |
| Purity | ≥99%(HPLC) |
| CASNumber | 162112-37-0 |
| PubChemID | 9953357 |
| InChIKey | HOFGTYCLOKDAES-UHFFFAOYSA-N |
| Smiles | CC1=C(C(NCCCO)=O)C=NN1C2=NC(C3=CC(C(F)(F)F)=CC=C3)=CS2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 41.04 | 100 | |
| ethanol | 4.1 | 10 |
Thefollowingdataisbasedontheproductmolecularweight410.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.44mL | 12.18mL | 24.37mL |
| 5mM | 0.49mL | 2.44mL | 4.87mL |
| 10mM | 0.24mL | 1.22mL | 2.44mL |
| 50mM | 0.05mL | 0.24mL | 0.49mL |



