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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/RU 28318, potassium salt/1672/10/10 mg
产品编号:1672/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/RU 28318, potassium salt/1672/10/10 mg
商品介绍
Description:Potent,selectivemineralocorticoidreceptorantagoNIST
AlternativeNames:Oxprenoatepotassium
ChemicalName:(7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylicacid,potassiumsalt
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectiveantagonistforthemineralocorticoidreceptor(MR).Inhibitsaldosteroneproductionandsecretion,andselectivelydecreasesex-vivoMRbindinginthehippocampusofadrenalectomisedrats.Alsodecreasesbloodpressureinfemaleratsfollowingcentraladministrationinvivo.

TechnicalData

M.Wt440.66
FormulaC25H37O4K
StorageDesiccateat+4°C
Purity≥98%(HPLC)
CASNumber76676-34-1
PubChemID23677972
InChIKeyHXJITUGMCJCKCE-UYOQDFFISA-M
Smiles[K+].[H][C@@]12CC[C@@](O)(CCC([O-])=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])[C@H](CCC)CC2=CC(=O)CC[C@]12C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO4.4110
ethanol44.07100
water44.07100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight440.66.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.27mL11.35mL22.69mL
5mM0.45mL2.27mL4.54mL
10mM0.23mL1.13mL2.27mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet