PotentagonistofS1P1receptors(EC50=9pM).InducesinternalizationandpolyubiquitinationofS1P1invitro.SelectiveforS1P1overS1P2-S1P4.
RP001hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 468.93 |
Formula | C24H24N4O4.HCl |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 1306761-53-4 |
PubChemID | 90488927 |
InChIKey | ZHPGSGYEFGEZAL-UHFFFAOYSA-N |
Smiles | CC(C)OC1=C(C#N)C=C(C2=NC(C3=C(CCC4NCCC(O)=O)C4=CC=C3)=NO2)C=C1.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 43.25 | 100 |
Thefollowingdataisbasedontheproductmolecularweight468.93.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.13mL | 10.66mL | 21.33mL |
5mM | 0.43mL | 2.13mL | 4.27mL |
10mM | 0.21mL | 1.07mL | 2.13mL |
50mM | 0.04mL | 0.21mL | 0.43mL |