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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Lalistat 1/6098/50/50 mg
产品编号:6098/50
市  场 价:¥15580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$779.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Lalistat 1/6098/50/50 mg
商品介绍
Description:Potentandselectivelysosomalacidlipase(LAL)inhibitor
ChemicalName:4-(Piperidin-1-yl)-1,2,5-thiADIazol-3-ylmorpholine-4-carboxylate
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivelysosomalacidlipase(LAL)inhibitor(IC50=68nM).Exhibitsnosignificantactivityagainstpancreaticlipaseorlipoproteinlipaseat10μMconcentration.BlocksLAL-mediatedlipidhydrolysisofacetylatedLDLandreduceseffluxofcholesterolfromlipid-loadedcellsresultinginincreasedcellularcholesterolesterlevels.

TechnicalData

M.Wt298.36
FormulaC12H18N4O3S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber501104-16-1
PubChemID648404
InChIKeyGKOPFXFKPASEFI-UHFFFAOYSA-N
SmilesO=C(OC1=NSN=C1N2CCCCC2)N3CCOCC3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO29.84100
ethanol29.84100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight298.36.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.35mL16.76mL33.52mL
5mM0.67mL3.35mL6.7mL
10mM0.34mL1.68mL3.35mL
50mM0.07mL0.34mL0.67mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet