Inhibitorofdiacylglycerollipase(IC50valuesare1.1and4μMinratcardiacmyocytesandcanineplateletsrespectively).WeaklyinhibitsphospholipasesCandA2.Potentiatesacetylcholineevokedrelaxationinmesentericarteriesbytheinhibitionofcholinesteraseactivity(IC50=4μM).
RHC80267isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 394.51 |
Formula | C20H34N4O4 |
Storage | Storeat+4°C |
Purity | ≥95%(HPLC) |
CASNumber | 83654-05-1 |
PubChemID | 5063 |
InChIKey | RXSVYGIGWRDVQC-UHFFFAOYSA-N |
Smiles | O=C(NCCCCCCNC(O/N=C2CCCCC2)=O)O/N=C1CCCCC/1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 39.45 | 100 | |
ethanol | 39.45 | 100 |
Thefollowingdataisbasedontheproductmolecularweight394.51.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.53mL | 12.67mL | 25.35mL |
5mM | 0.51mL | 2.53mL | 5.07mL |
10mM | 0.25mL | 1.27mL | 2.53mL |
50mM | 0.05mL | 0.25mL | 0.51mL |