Nrf2activator;inhibitsNrf2/Keap1interaction(Kd=6μM).SuppressesLPS-inducediNOSandnitricoxideexpressioninmacrophages.Anti-inflammatory.
| M.Wt | 452.57 |
| Formula | C25H28N2O4S |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 1832713-02-6 |
| PubChemID | 91971266 |
| InChIKey | BVYWIQHJXAEJOD-IBGZPJMESA-N |
| Smiles | CC1=C(C)C=C(C)C(C)=C1S(=O)(NC2=C(C=CC=C3)C3=C(N4C[C@@H](C(O)=O)CC4)C=C2)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 45.26 | 100 | |
| ethanol | 4.53 | 10mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight452.57.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.21mL | 11.05mL | 22.1mL |
| 5mM | 0.44mL | 2.21mL | 4.42mL |
| 10mM | 0.22mL | 1.1mL | 2.21mL |
| 50mM | 0.04mL | 0.22mL | 0.44mL |



