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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/R18/2144/1/1 mg
产品编号:2144/1
市  场 价:¥6180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$309.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/R18/2144/1/1 mg
商品介绍
Description:Inhibitorof14.3.3proteins
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AntagoNISTof14.3.3proteins(KD≈80nM).Competitivelyinhibits14.3.3-ligandinteractionswithoutrequiringphosphorylation.BlockstheABIlityof14.3.3tobindtotargetproteinssuchasRaf-1,Bad,ASK1andexoenzymeS.

TechnicalData

M.Wt2309.69
FormulaC101H157N27O29S3
SequencePHCVPRDLSWLDLEANMCLP
StorageDesiccateat-20°C
CASNumber211364-78-2
PubChemID16138697
InChIKeyYSKZRNFKZLWXRG-ZHTKBQOPSA-N
Smiles[H]N1CCC[C@H]1C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CS)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight2309.69.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.43mL2.16mL4.33mL
5mM0.09mL0.43mL0.87mL
10mM0.04mL0.22mL0.43mL
50mM0.01mL0.04mL0.09mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet