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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/R 568 hydrochloride/3815/10/10 mg
产品编号:3815/10
市  场 价:¥3100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$155.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/R 568 hydrochloride/3815/10/10 mg
商品介绍
Description:Positiveallostericmodulatorofthehumancalcium-sensingreceptor
ChemicalName:2-Chloro-N-[(1R)-1-(3-methoxyphenyl)ethyl]-benzenepropanaminehydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PositiveallostericmodulatorandallostericagoNISTofthehumancalcium-sensingreceptor(hCaSR).Exhibitscalcimimeticactivity.HastheABIlitytorestorefunctiontohCaSRmutantsthatcausefamilialhypocalciurichypercalcemia(FHH)andneonatalseverehyperparathyroidism(NSHPT).Exertsasuppressiveeffectonparathyroid(PT)hormonesecretion;inhibitsPTcellproliferationinratswithrenalinsufficiency.

CompoundLibraries

R568hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt340.29
FormulaC18H22ClNO.HCl
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber177172-49-5
PubChemID158796
InChIKeyYJXUXANREVNZLH-PFEQFJNWSA-N
SmilesClC(C=CC=C2)=C2CCCN[C@H](C)C1=CC=CC(OC)=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO34.03100
ethanol34.03100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight340.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.94mL14.69mL29.39mL
5mM0.59mL2.94mL5.88mL
10mM0.29mL1.47mL2.94mL
50mM0.06mL0.29mL0.59mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet