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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/QS 11/3324/50/50 mg
产品编号:3324/50
市  场 价:¥15300.00
场      地:美国(厂家直采)
产品分类: 蛋白类>天然蛋白>球蛋白>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$765.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/QS 11/3324/50/50 mg
商品介绍
Description:ARFGAP1inhibitor;modulatesWnt/β-cateninsignaling
ChemicalName:(2S)-2-[2-(Indan-5-yloxy)-9-(1,1'-biphenyl-4-yl)methyl)-9H-purin-6-ylamino]-3-phenyl-propan-1-ol
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GTPaseactivatingproteinofADP-ribosylationfactor1(ARFGAP1)inhibitor.ModulatesARF-GTPlevelsandsynergizeswiththeWnt/β-cateninsignalingpathwaytoupregulateβ-cateninnucleartranslocation.Alsoreducesinvitromigrationofmetastatichumanbreastcancercells.

TechnicalData

M.Wt567.68
FormulaC36H33N5O2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber944328-88-5
PubChemID42623900
InChIKeyDOKZLKDGUQWMSX-HKBQPEDESA-N
SmilesOC[C@H](CC6=CC=CC=C6)NC1=C2C(N(CC3=CC=C(C7=CC=CC=C7)C=C3)C=N2)=NC(OC4=CC=C(CCC5)C5=C4)=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO56.77100
ethanol56.77100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight567.68.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.76mL8.81mL17.62mL
5mM0.35mL1.76mL3.52mL
10mM0.18mL0.88mL1.76mL
50mM0.04mL0.18mL0.35mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet