Enhancessurvivalofhumanembryonicstemcells(hESCs)followingenzymaticdissociation.Thoughttoenhancecell-ECMadhesionandactivateintegrinsignaling.IncreasesadhesionofhESCstomatrigel-andlaminin-coatedplates,butnottogelatin-coatedplates.Alsopodocyte-protectiveagentandpreventsLPS-inducedproteinuriainmice.
PyrintegrinisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 451.54 |
Formula | C23H25N5O3S |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 1228445-38-2 |
PubChemID | 46223724 |
InChIKey | QRJTZIJWDLJKQO-UHFFFAOYSA-N |
Smiles | OC(C=C3)=CC2=C3N(CCC2)C1=NC(NC4=CC=C(S(NCC5CC5)(=O)=O)C=C4)=NC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 45.15 | 100 |
Thefollowingdataisbasedontheproductmolecularweight451.54.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.21mL | 11.07mL | 22.15mL |
5mM | 0.44mL | 2.21mL | 4.43mL |
10mM | 0.22mL | 1.11mL | 2.21mL |
50mM | 0.04mL | 0.22mL | 0.44mL |