Proteinsynthesisinhibitor;leadstotheprematurereleaseofpolypeptidechainsaspolypeptidylpurinederivatives.Analogofthe3'endofaminoacyl-tRNA.Aminonucleosideantibiotic.Inhibitstranslationinbothinvitroandinvivosystems.Alsoinhibitsthetransportofproteinsintothemitochondriainvitro.
M.Wt | 544.43 |
Formula | C22H29N7O5.2HCl |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 58-58-2 |
PubChemID | 443311 |
InChIKey | MKSVFGKWZLUTTO-FZFAUISWSA-N |
Smiles | O[C@@H]1[C@H](NC([C@@H](N)CC4=CC=C(OC)C=C4)=O)[C@@H](CO)O[C@H]1N3C2=NC=NC(N(C)C)=C2N=C3.Cl.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 54.44 | 100 | |
water | 54.44 | 100 |
Thefollowingdataisbasedontheproductmolecularweight544.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 1.84mL | 9.18mL | 18.37mL |
5mM | 0.37mL | 1.84mL | 3.67mL |
10mM | 0.18mL | 0.92mL | 1.84mL |
50mM | 0.04mL | 0.18mL | 0.37mL |