Proteinsynthesisinhibitor;leadstotheprematurereleaseofpolypeptidechainsaspolypeptidylpurinederivatives.Analogofthe3'endofaminoacyl-tRNA.Aminonucleosideantibiotic.Inhibitstranslationinbothinvitroandinvivosystems.Alsoinhibitsthetransportofproteinsintothemitochondriainvitro.
| M.Wt | 544.43 |
| Formula | C22H29N7O5.2HCl |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 58-58-2 |
| PubChemID | 443311 |
| InChIKey | MKSVFGKWZLUTTO-FZFAUISWSA-N |
| Smiles | O[C@@H]1[C@H](NC([C@@H](N)CC4=CC=C(OC)C=C4)=O)[C@@H](CO)O[C@H]1N3C2=NC=NC(N(C)C)=C2N=C3.Cl.Cl |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 54.44 | 100 | |
| water | 54.44 | 100 |
Thefollowingdataisbasedontheproductmolecularweight544.43.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 1.84mL | 9.18mL | 18.37mL |
| 5mM | 0.37mL | 1.84mL | 3.67mL |
| 10mM | 0.18mL | 0.92mL | 1.84mL |
| 50mM | 0.04mL | 0.18mL | 0.37mL |



