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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Piperlongumine/4396/10/10 mg
产品编号:4396/10
市  场 价:¥3380.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$169.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Piperlongumine/4396/10/10 mg
商品介绍
Description:Inducesapoptosis;increasesp53andROSlevelsincancercells
ChemicalName:5,6-Dihydro-1-[(2E)-1-oxo-3-(3,4,5-trimethoxyphenyl)-2-propen-1-yl]-2(1H)-pyridinone
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Inducescelldeathandincreasesthelevelofreactiveoxygenspecies(ROS)incancercellswithbothwild-typeandnormalp53.Alsoinhibitsthegrowthofspontaneousmalignantbreasttumorsinmice.Displayslittleeffectonnormalcells.RapidlydepletesandrogenreceptorexpressioninhumanprostatecancercellsviaaROS-dependent,proteasome-mediatedmechanism.

TechnicalData

M.Wt317.34
FormulaC17H19NO5
StorageStoreat-20°C
Purity≥97%(HPLC)
CASNumber20069-09-4
PubChemID637858
InChIKeyVABYUUZNAVQNPG-BQYQJAHWSA-N
SmilesO=C1N(C(/C=C/C2=CC(OC)=C(OC)C(OC)=C2)=O)CCC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO31.73100
ethanol6.3520mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight317.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.15mL15.76mL31.51mL
5mM0.63mL3.15mL6.3mL
10mM0.32mL1.58mL3.15mL
50mM0.06mL0.32mL0.63mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet