Highlypotentmelatoninagonist;displayshigheraffinityandgreaterpotencythanmelatoninitself.TheEC50valuesforGproteinactivationinMT1andMT2-transfectedcellsare65and58pMrespectively.
2-PhenylmelatoninisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
M.Wt | 308.38 |
Formula | C19H20N2O2 |
Storage | Desiccateat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 151889-03-1 |
PubChemID | 4018512 |
InChIKey | OFCLARYYBGKCHN-UHFFFAOYSA-N |
Smiles | COC1=CC=C2NC(=C(CCNC(C)=O)C2=C1)C1=CC=CC=C1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 30.84 | 100 | |
ethanol | 30.84 | 100 |
Thefollowingdataisbasedontheproductmolecularweight308.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.24mL | 16.21mL | 32.43mL |
5mM | 0.65mL | 3.24mL | 6.49mL |
10mM | 0.32mL | 1.62mL | 3.24mL |
50mM | 0.06mL | 0.32mL | 0.65mL |