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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/OB 24 hydrochloride/6119/50/50 mg
产品编号:6119/50
市  场 价:¥12180.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$609.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/OB 24 hydrochloride/6119/50/50 mg
商品介绍
Description:Potentandselectivehemeoxygenase1(HO-1)inhibitor
ChemicalName:1-[[2-[2-(4-Bromophenyl)ethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazolehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectivehemeoxygenase1(HO-1)inhibitor(IC50valuesare1.9and>100μMforHO-1andHO-2respectively),reducesproteincarbonylationandreactiveoxygenspeciesformationinadvancedprostatecancercells(PCA).InhibitscellproliferationinvitroandPCAtumorgrowthandlymphnode/lungmetastasesinvivo.SynergizeswithTaxol(Cat.No.1097).

TechnicalData

M.Wt373.67
FormulaC15H17BrN2O2.HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber939825-12-4
PubChemID45265865
InChIKeyYSOWYXRHOAXXTG-UHFFFAOYSA-N
SmilesBrC1=CC=C(C=C1)CCC2(OCCO2)CN3C=CN=C3.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.37100
water37.37100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight373.67.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.68mL13.38mL26.76mL
5mM0.54mL2.68mL5.35mL
10mM0.27mL1.34mL2.68mL
50mM0.05mL0.27mL0.54mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet