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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PRIMA-1/1862/10/10 mg
产品编号:1862/10
市  场 价:¥2580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PRIMA-1/1862/10/10 mg
商品介绍
Description:Restoresmutantp53activity;inducesapoptosis
ChemicalName:2,2-Bis(hydroxymethyl)-1-azABIcyclo[2.2.2]octan-3-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivelyrestoresmutantp53activityintumorcellsviaactivationofBaxandPUMA.Inducesapoptosisandinhibitsgrowthoftumorswithmutantp53.

TechnicalData

M.Wt185.22
FormulaC9H15NO3
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber5608-24-2
PubChemID322968
InChIKeyRFBVBRVVOPAAFS-UHFFFAOYSA-N
SmilesO=C1C(CO)(CO)N2CCC1CC2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
phosphatebufferedsaline18.52100
water18.52100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight185.22.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM5.4mL26.99mL53.99mL
5mM1.08mL5.4mL10.8mL
10mM0.54mL2.7mL5.4mL
50mM0.11mL0.54mL1.08mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet