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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PMX 53/5473/1/1 mg
产品编号:5473/1
市  场 价:¥4700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$235.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PMX 53/5473/1/1 mg
商品介绍
Description:PotentC5areceptorantagoNIST
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentC5areceptorantagonist(IC50=20nM).AlsoMrgX2agonist.StimulatesMrgX2-mediatedmastcelldegranulation.AlsoinhibitsC5a-inducedhypernociceptioninrats,inhibitslungmetastasisinamousebreastcancermodelandreducesatheroscleroticlesionsinamousemodelofatherosclerosis.

TechnicalData

M.Wt896.1
FormulaC47H65N11O7
SequenceFXPXWR

(Modifications:Phe-1=N-terminalAc,X-2=Orn,X-4=D-Cha,Lactambridge:Orn-2toArg-6)

StorageStoreat-20°C
CASNumber219639-75-5
PubChemID23526550
InChIKeyYOKBGCTZYPOSQM-UHFFFAOYSA-N
SmilesNC(=NCCCC1NC(=O)C(NC(=O)C(CC2CCCCC2)NC(=O)C2N(C(=O)C(CCCNC1=O)NC(=O)C(Cc1ccccc1)NC(=O)C)CCC2)Cc1c[nH]c2c1cccc2)N

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto2mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight896.1.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.12mL5.58mL11.16mL
5mM0.22mL1.12mL2.23mL
10mM0.11mL0.56mL1.12mL
50mM0.02mL0.11mL0.22mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet