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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PMX 205/5196/1/1 mg
产品编号:5196/1
市  场 价:¥5300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$265.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PMX 205/5196/1/1 mg
商品介绍
Description:PotentC5areceptorpeptideantagoNIST
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentC5areceptorpeptideantagonist(IC50=31nM).Amelioratesexperimentally-inducedcoloninflammationinmice.Reducesfibrillaramyloiddeposits,decreaseshyperphosphorylatedtaulevelsandrescuescognitivefunctioninamousemodelofAlzheimer'sDisease.Orallyactiveandbrainpenetrant.

TechnicalData

M.Wt839.05
FormulaC45H62N10O6
SequenceXPXWR

(Modifications:X-1=N2-(1-Oxo-3-phenylpropyl)-Orn,X-3=D-Cha,Lactambridge:Orn-1toArg-5)

StorageStoreat-20°C
CASNumber514814-49-4
PubChemID90489023
InChIKeyYUIBSMOWXFHTBD-UHFFFAOYSA-N
SmilesNC(=N)NCCCC1NC(=O)C(CC2C=NC3=CC=CC=C23)NC(=O)C(CC2CCCCC2)NC(=O)C2CCCN2C(=O)C(CCCNC1=O)NC(=O)CCC1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto1mg/mlinwaterwithsonication

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight839.05.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM1.19mL5.96mL11.92mL
5mM0.24mL1.19mL2.38mL
10mM0.12mL0.6mL1.19mL
50mM0.02mL0.12mL0.24mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet