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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PMPA (NAALADase inhibitor)/1380/50/50 mg
产品编号:1380/50
市  场 价:¥11580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$579.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PMPA (NAALADase inhibitor)/1380/50/50 mg
商品介绍
Description:GCPIIinhibitor
ChemicalName:2-(Phosphonomethyl)pentane-1,5-dioicacid
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highlypotentandselectiveinhibitorof glutamatecarboxypeptidase2(GCPII/N-acetylatedα-linkeddipeptidase/NAALADase)withaKivalueof275pM.Neuroprotective;protectsagainstglutamate-mediatedmotorneurondegenerationandreducesvolumeofinjuryfollowingmiddlecerebralarteryocclusion(MCAO).

LicensingInformation

SoldwiththepermissionofAstraZenecaLtd.

TechnicalData

M.Wt226.12
FormulaC6H11O7P
StorageDesiccateatRT
CASNumber173039-10-6
PubChemID10130754
InChIKeyISEYJGQFXSTPMQ-UHFFFAOYSA-N
SmilesOC(=O)CCC(CP(=O)(O)O)C(O)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water22.61100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight226.12.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.42mL22.11mL44.22mL
5mM0.88mL4.42mL8.84mL
10mM0.44mL2.21mL4.42mL
50mM0.09mL0.44mL0.88mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet