Syntheticmyelinproteolipidprotein(PLP)fragment.Immunizationwiththispeptideinducessevereclinicalandhistologicalexperimentalallergicencephalomyelitis(EAE),ananimalmodelofmultiplesclerosis.
| M.Wt | 1521.74 |
| Formula | C72H104N20O17 |
| Sequence | HSLGKWLGHPDKF |
| Storage | Desiccateat-20°C |
| CASNumber | 122018-58-0 |
| PubChemID | 16199055 |
| InChIKey | UQIBUOXNUPHALR-UVIWMAFZSA-N |
| Smiles | [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC1=CNC=N1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CC=CC=C1)C(O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solubility | Solubleto2mg/mlinwater |
Thefollowingdataisbasedontheproductmolecularweight1521.74.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 0.66mL | 3.29mL | 6.57mL |
| 5mM | 0.13mL | 0.66mL | 1.31mL |
| 10mM | 0.07mL | 0.33mL | 0.66mL |
| 50mM | 0.01mL | 0.07mL | 0.13mL |



