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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PF 998425/3923/10/10 mg
产品编号:3923/10
市  场 价:¥3980.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$199.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PF 998425/3923/10/10 mg
商品介绍
Description:Non-steroidalandrogenreceptorantagoNIST
ChemicalName:4-((1R,2R)-2-Hydroxycyclohexyl)-2(trifluoromethyl)benzonitrile
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivenon-steroidalandrogenreceptor(AR)antagonist(IC50valuesare26nMand90nMinARbindingassaysandcellularassaysrespectively).Displayslowaffinityforprogesteronereceptor(IC50>10μM).Activeinvivo.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt269.26
FormulaC14H14F3NO
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1076225-27-8
PubChemID25093231
InChIKeyMENRRRXHFQYXDW-DGCLKSJQSA-N
SmilesO[C@H](CCCC2)[C@H]2[C@]1=CC(C(F)(F)F)=C(C#N)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO26.93100
ethanol26.93100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight269.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.71mL18.57mL37.14mL
5mM0.74mL3.71mL7.43mL
10mM0.37mL1.86mL3.71mL
50mM0.07mL0.37mL0.74mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet