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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PF 4981517/4252/50/50 mg
产品编号:4252/50
市  场 价:¥21700.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$1085.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PF 4981517/4252/50/50 mg
商品介绍
Description:SelectiveCYP3A4inhibitor
ChemicalName:(1-Methyl-3-[1-methyl-5-(4-methylphenyl)-1H-pyrazol-4-yl]-4-[(3S)-3-piperidin-1-ylpyrrolidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine)
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveinhibitorofCYP3A4(IC50valuesare0.03,17and70μMforCYP3A4,CYP3A5andCYP3A7respectively).

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

TechnicalData

M.Wt456.59
FormulaC26H32N8
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1390637-82-7
PubChemID71315139
InChIKeyWDWIMDKOXZZYHH-FQEVSTJZSA-N
SmilesCN1N=C(C5=C(C6=CC=C(C)C=C6)N(C)N=C5)C2=C1N=CN=C2N3C[C@@H](N4CCCCC4)CC3

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO45.66100
ethanol9.1320

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight456.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.19mL10.95mL21.9mL
5mM0.44mL2.19mL4.38mL
10mM0.22mL1.1mL2.19mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet