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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PCA 4248/0571/50/50 mg
产品编号:0571/50
市  场 价:¥10700.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$535.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PCA 4248/0571/50/50 mg
商品介绍
Description:PAFreceptorantagoNIST
ChemicalName:1,4-Dihydro-2,4,6-trimethyl-3,5-pyridinedicarboxylicacidmethyl2-(phenylthio)ethylester
Purity:≥95%
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

AspecificPAFantagonist,morepotentthantheginkolideBN-52021.InhibitsrabbitplateletaggregationwithanIC50valueof1.05μMandhasnosignificantactivityonCa2+channels.Activeinvivo,antagonizingPAF-inducedsystemichypotensionandprotein-plasmaextravasationinrats.

CompoundLibraries

PCA4248isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt361.46
FormulaC19H23NO4S
StorageDesiccateat-20°C
Purity≥95%
CASNumber123875-01-4
PubChemID4698
InChIKeyDHCNAWNKZMNTIS-UHFFFAOYSA-N
SmilesCOC(=O)C1=C(C)NC(C)=C(C1C)C(=O)OCCSC1=CC=CC=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO36.14100
ethanol36.14100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight361.46.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.77mL13.83mL27.67mL
5mM0.55mL2.77mL5.53mL
10mM0.28mL1.38mL2.77mL
50mM0.06mL0.28mL0.55mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet