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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PB 28 dihydrochloride/2562/10/10 mg
产品编号:2562/10
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PB 28 dihydrochloride/2562/10/10 mg
商品介绍
Description:Highaffinityσ2agoNIST
ChemicalName:1-Cyclohexyl-4-[3-(1,2,3,4-tetrahydro-5-methoxy-1-naphthalenyl)propyl]piperazinedihydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Highaffinityσ2receptoragonist(Kivaluesare0.8and15.2nMforσ2andσ1receptorsrespectively)thatdisplaysminimalaffinityatotherreceptors.Inhibitselectricallyevokedtwitchinguineapigbladderandileum(EC50valuesare2.62and3.96μMrespectively).DisplaysantiproliferativeandcytotoxiceffectsinSK-N-SHneuroblastomaandC6gliomacells.

TechnicalData

M.Wt443.5
FormulaC24H38N2O.2HCl
StorageDesiccateat+4°C
Purity≥99%(HPLC)
CASNumber172907-03-8
PubChemID46861545
InChIKeyDSRBJOQIBXACIV-UHFFFAOYSA-N
SmilesO=C1C=C(C)C(/C(C)=N/C2=C(N)C=CC=C2)=C(O)N1O.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
water8.8720mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight443.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.25mL11.27mL22.55mL
5mM0.45mL2.25mL4.51mL
10mM0.23mL1.13mL2.25mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet