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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/PA 452/5086/50/50 mg
产品编号:5086/50
市  场 价:¥18500.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$925.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/PA 452/5086/50/50 mg
商品介绍
Description:RXRantagoNIST
ChemicalName:2-[[3-(Hexyloxy)-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl]methylamino]-5-pyrimidinecarboxylicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

RXRantagonist(pA2=7.11).TriggersdissociationofRXRtetramers.AttenuatescellproliferationandinducesapoptosisinMCF-7breastcancercells.

CompoundLibraries

PA452isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt439.59
FormulaC26H37N3O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber457657-34-0
PubChemID9803242
InChIKeyJJUUTJCZMGZJDZ-UHFFFAOYSA-N
SmilesCC1(C)C2=C(C=C(N(C3=NC=C(C(O)=O)C=N3)C)C(OCCCCCC)=C2)C(C)(C)CC1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO43.96100
ethanol4.410

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight439.59.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.27mL11.37mL22.75mL
5mM0.45mL2.27mL4.55mL
10mM0.23mL1.14mL2.27mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet