Antitumoragentthatformsplatinum-DNAadducts.Causesintra-andinterstrandDNAcrosslinksblockingDNAreplicationandtranscription.Displayshighercytotoxicityandlowernephrotoxicitythananalogcisplatin(Cat.No.2251)andshowsantitumoractivityincelllineswithacquiredcisplatinresistance.
M.Wt | 397.29 |
Formula | C8H14N2O4Pt |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 61825-94-3 |
PubChemID | 9887054 |
InChIKey | ZROHGHOFXNOHSO-BNTLRKBRSA-L |
Smiles | [Pt++].[O-]C(=O)C([O-])=O.[H][C@@]1(N)CCCC[C@@]1([H])N |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
water | 1.99 | 5mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight397.29.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.52mL | 12.59mL | 25.17mL |
5mM | 0.5mL | 2.52mL | 5.03mL |
10mM | 0.25mL | 1.26mL | 2.52mL |
50mM | 0.05mL | 0.25mL | 0.5mL |