请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Oleanolic acid/6026/50/50 mg
产品编号:6026/50
市  场 价:¥1300.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$65.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Oleanolic acid/6026/50/50 mg
商品介绍
Description:SelectiveGPBAreceptor(TGR5)partialagoNIST
ChemicalName:(3β)-3-Hydroxyolean-12-en-28-oicacid
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GPBAreceptor(TGR5)partialagonist(EC50=2.25μM;72%efficacy).DisplaysnoactivityatFXR.Alsoinhibitsproteinphosphate1B(PTP1B)andglycogenphosphorylase.SuppressescellproliferationandincreasesapoptosisinT24bladdercancercells.Antidiabetic,antihyperglycaemic,antitumorandhepatoprotective.

TechnicalData

M.Wt456.7
FormulaC30H48O3
StorageStoreat+4°C
Purity≥97%(HPLC)
CASNumber508-02-1
PubChemID10494
InChIKeyMIJYXULNPSFWEK-GTOFXWBISA-N
Smiles[H][C@@]12CC(C)(CC[C@]1(C(O)=O)CC[C@@]3(C2=CC[C@@]4([C@]5(CC[C@@H](C(C)([C@@]5(CC[C@@]34C)[H])C)O)C)[H])C)C

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO9.1320mMwithgentlewarming
ethanol4.5710mMwithgentlewarming

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight456.7.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.19mL10.95mL21.9mL
5mM0.44mL2.19mL4.38mL
10mM0.22mL1.09mL2.19mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet