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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/ONO 1078/3026/50/50 mg
产品编号:3026/50
市  场 价:¥1900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/ONO 1078/3026/50/50 mg
商品介绍
Description:SelectiveCysLT1antagoNIST
AlternativeNames:Pranlukast
ChemicalName:N-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-1-benzopyran-8-yl]-4(4-phenylbutoxy)benzamide
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Selectivecysteinylleukotrienereceptor1(CysLT1)antagonist(IC50valuesare~4-7and3620nMforCysLT1andCysLT2respectively).Inhibitscontractionofairwaysmoothmuscle,microvascularleakageintoairwaysandeosinophilinfiltration.Candecreasesymptomsofbronchialasthma.

TechnicalData

M.Wt481.5
FormulaC27H23N5O4
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber103177-37-3
PubChemID4887
InChIKeyNBQKINXMPLXUET-UHFFFAOYSA-N
SmilesO=C2C1=CC=CC(NC(C4=CC=C(OCCCCC5=CC=CC=C5)C=C4)=O)=C1OC(C3=NN=NN3)=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO24.0750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight481.5.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.08mL10.38mL20.77mL
5mM0.42mL2.08mL4.15mL
10mM0.21mL1.04mL2.08mL
50mM0.04mL0.21mL0.42mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet