请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/OF 1/5289/10/10 mg
产品编号:5289/10
市  场 价:¥3900.00
场      地:美国(厂家直采)
产品分类: 蛋白类>多肽>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$195.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/OF 1/5289/10/10 mg
商品介绍
Description:SelectiveBRPF1BandBRPF2inhibitor
ChemicalName:4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methylbenzenesulfonamide
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveBRPF1BandBRPF2bromodomaininhibitor(Kdvaluesare100and500nMrespectively).Exhibits39-foldselectivityforBRPF1BandBRPF2overBRD4.AcceleratesFRAPrecoveryat5μMinaBRPF2FRAPassay.

LicensingInformation

ThisprobeissuppliedinconjunctionwiththeStructuralGenomicsConsortium.Forfurthercharacterizationdetails,pleasevisittheOF1probesummaryontheSGCwebsite.

CompoundLibraries

OF1isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt440.31
FormulaC17H18BrN3O4S
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber919973-83-4
PubChemID35397514
InChIKeyYUNQZQREIHWDQT-UHFFFAOYSA-N
SmilesCN1C2=C(C=C(OC)C(NS(C3=C(C)C=C(Br)C=C3)(=O)=O)=C2)N(C)C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO8.8120

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight440.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.27mL11.36mL22.71mL
5mM0.45mL2.27mL4.54mL
10mM0.23mL1.14mL2.27mL
50mM0.05mL0.23mL0.45mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet