Oct4activator;enhancesiPSCreprogrammingfour-foldandacceleratestheappearanceofiPSCcoloniesincombinationwith4F(Oct4,Sox2,c-MycandKlf4).Alsoinducescardiomyocyte-likecellsfromhumanfibroblasts,aspartofthe9Ccocktail(CHIR99021,A83-01,BIX01294,AS83541,SC1,Y27632,SU16f,JNJ10198409andOAC-2)
M.Wt | 236.27 |
Formula | C15H12N2O |
Storage | Storeat+4°C |
Purity | ≥98%(HPLC) |
CASNumber | 6019-39-2 |
PubChemID | 2814138 |
InChIKey | JCAFGYWSIWYMOX-UHFFFAOYSA-N |
Smiles | O=C(C1=CC=CC=C1)NC2=CC=C3C(C=CN3)=C2 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 23.63 | 100 | |
ethanol | 23.63 | 100 |
Thefollowingdataisbasedontheproductmolecularweight236.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.23mL | 21.16mL | 42.32mL |
5mM | 0.85mL | 4.23mL | 8.46mL |
10mM | 0.42mL | 2.12mL | 4.23mL |
50mM | 0.08mL | 0.42mL | 0.85mL |