Oct3/4inducer;promotesOct3/4expressionandstABIlizestheOct3/4proteininHEK293cells.Inducesexpressionofpluripotent-associatedgenesLin28,Sox2andNanog,andsuppressesRex1.Induces15-foldincreaseinOct3/4expressioninhumanprimaryfibroblasts.
O4I2isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 282.75 |
| Formula | C12H11ClN2O2S |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 165682-93-9 |
| PubChemID | 53428670 |
| InChIKey | ULUBAPWNHROTEU-UHFFFAOYSA-N |
| Smiles | ClC(C=C2)=CC=C2NC1=NC(C(OCC)=O)=CS1 |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 28.27 | 100 | |
| ethanol | 14.14 | 50 |
Thefollowingdataisbasedontheproductmolecularweight282.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 3.54mL | 17.68mL | 35.37mL |
| 5mM | 0.71mL | 3.54mL | 7.07mL |
| 10mM | 0.35mL | 1.77mL | 3.54mL |
| 50mM | 0.07mL | 0.35mL | 0.71mL |



