Glucosidaseinhibitor(IC50valuesare0.42and8.4μMforacidα-glucosidaseandα-1,6-glucosidaserespectively).Inhibitsliverglycogenbreakdowninvivo.Alsoactsasachemicalchaperone;chaperonesβ-Glufoldingatneutralp.H.allowingthestABIlizedenzymetotransitfromtheendoplasmicreticulumtothegolgi,enablingpropertraffickingtothelysosome.
M.Wt | 289.41 |
Formula | C15H31NO4 |
Storage | Storeat-20°C |
CASNumber | 81117-35-3 |
PubChemID | 501640 |
InChIKey | FTSCEGKYKXESFF-LXTVHRRPSA-N |
Smiles | O[C@H]1[C@H](O)[C@@H](CO)N(CCCCCCCCC)C[C@@H]1O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 28.94 | 100 | |
ethanol | 28.94 | 100 |
Thefollowingdataisbasedontheproductmolecularweight289.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 3.46mL | 17.28mL | 34.55mL |
5mM | 0.69mL | 3.46mL | 6.91mL |
10mM | 0.35mL | 1.73mL | 3.46mL |
50mM | 0.07mL | 0.35mL | 0.69mL |