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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/N-Nonyldeoxynojirimycin/3691/10/10 mg
产品编号:3691/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/N-Nonyldeoxynojirimycin/3691/10/10 mg
商品介绍
Description:Glucosidaseinhibitor
AlternativeNames:NN-DNJ
ChemicalName:(2R,3R,4R,5S)-2-(Hydroxymethyl)-1-nonyl-3,4,5-piperidinetriol
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Glucosidaseinhibitor(IC50valuesare0.42and8.4μMforacidα-glucosidaseandα-1,6-glucosidaserespectively).Inhibitsliverglycogenbreakdowninvivo.Alsoactsasachemicalchaperone;chaperonesβ-Glufoldingatneutralp.H.allowingthestABIlizedenzymetotransitfromtheendoplasmicreticulumtothegolgi,enablingpropertraffickingtothelysosome.

TechnicalData

M.Wt289.41
FormulaC15H31NO4
StorageStoreat-20°C
CASNumber81117-35-3
PubChemID501640
InChIKeyFTSCEGKYKXESFF-LXTVHRRPSA-N
SmilesO[C@H]1[C@H](O)[C@@H](CO)N(CCCCCCCCC)C[C@@H]1O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO28.94100
ethanol28.94100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight289.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.46mL17.28mL34.55mL
5mM0.69mL3.46mL6.91mL
10mM0.35mL1.73mL3.46mL
50mM0.07mL0.35mL0.69mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet