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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NSC 95397/1547/10/10 mg
产品编号:1547/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NSC 95397/1547/10/10 mg
商品介绍
Description:SelectiveCdc25dualspecificityphosphataseinhibitor
ChemicalName:2,3-bis[(2-Hydroxyethyl)thiol]-1,4-naphthoquinone
Purity:≥97%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveirreversIBLeinhibitorofCdc25dualspecificityphosphatases(Kivaluesare32,96and40nMforinhibitionofCdc25A,-Band-Crespectively).Displays125-180-foldselectivityoverVH1-relateddual-specificityphosphataseandproteintyrosinephosphatase1b.InhibitscarcinomacellgrowthandblocksG2/Mphasetransitioninvitro.

TechnicalData

M.Wt310.38
FormulaC14H14O4S2
StorageDesiccateat-20°C
Purity≥97%(HPLC)
CASNumber93718-83-3
PubChemID262093
InChIKeyMAASHDQFQDDECQ-UHFFFAOYSA-N
SmilesOCCSC1=C(SCCO)C(=O)C2=CC=CC=C2C1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO15.5250
ethanol1.555

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight310.38.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.22mL16.11mL32.22mL
5mM0.64mL3.22mL6.44mL
10mM0.32mL1.61mL3.22mL
50mM0.06mL0.32mL0.64mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet