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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NSC 87877/2613/50/50 mg
产品编号:2613/50
市  场 价:¥2780.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$139.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NSC 87877/2613/50/50 mg
商品介绍
Description:Potentinhibitorofshp2andshp1PTP
ChemicalName:8-Hydroxy-7-[(6-sulfo-2-naphthyl)azo]-5-quinolinesulfonicacid
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentinhibitorofshp2andshp1proteintyrosinephosphatases(PTP)(IC50valuesare0.318,0.355,1.691,7.745,65.617,84.473and150.930μMforshp2,shp1,PTP1B,HePTP,DEP1,CD45andLARrespectively).InhibitsEGF-inducedErk1/2activationinHEK293cellsandsignificantlyreducesMDA-MB-468cellviABIlity/proliferation.

TechnicalData

M.Wt459.45
FormulaC19H13N3O7S2
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber56990-57-9
PubChemID5459322
InChIKeyBIQBDHSYQMHHPU-CJLVFECKSA-N
SmilesOC2=C(/N=N/C3=CC=C(C=C(S(=O)(O)=O)C=C4)C4=C3)C=C(S(=O)(O)=O)C1=CC=CN=C12

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO9.1920
water22.9750

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight459.45.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.18mL10.88mL21.77mL
5mM0.44mL2.18mL4.35mL
10mM0.22mL1.09mL2.18mL
50mM0.04mL0.22mL0.44mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet