Wntsignalinginhibitor.BindsthePDZdomainoftheDishevelled(Dvl)protein.Inhibitsproliferation,migrationandTGF-β-induceddifferentiationoffibroblastsinvitro.Reducesseverityofpulmonaryfibrosisinamousemodel.
| M.Wt | 460.52 |
| Formula | C21H36N2O9 |
| Storage | Storeat-20°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 144678-63-7 |
| PubChemID | 71312060 |
| InChIKey | IPICFSFUAKDZEI-AJNGGQMLSA-N |
| Smiles | CC([C@@H](C(O)=O)OC([C@@H](NC([C@H](C(C)C)OC([C@@H](NC(OC(C)(C)C)=O)C)=O)=O)C)=O)C |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 46.05 | 100 | |
| ethanol | 46.05 | 100 |
Thefollowingdataisbasedontheproductmolecularweight460.52.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 2.17mL | 10.86mL | 21.71mL |
| 5mM | 0.43mL | 2.17mL | 4.34mL |
| 10mM | 0.22mL | 1.09mL | 2.17mL |
| 50mM | 0.04mL | 0.22mL | 0.43mL |



