Wernersyndromehelicase(WRN)helicaseinhibitor(IC50=250nM);actssynergisticallywithMitomycinC(Cat.No.3258)toinducedouble-strandbreaksandchromosomalabnormalitiesinvitro.
M.Wt | 400.04 |
Formula | C13H10Cl4N2O4 |
Storage | Storeat-20°C |
Purity | ≥98%(HPLC) |
CASNumber | 203115-63-3 |
PubChemID | 357621 |
InChIKey | PCOXPBOKDABARQ-UHFFFAOYSA-N |
Smiles | CC(CN1C(C(Cl)=C(Cl)C1=O)=O)(C)CN2C(C(Cl)=C(Cl)C2=O)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 8 | 20 |
Thefollowingdataisbasedontheproductmolecularweight400.04.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 2.5mL | 12.5mL | 25mL |
5mM | 0.5mL | 2.5mL | 5mL |
10mM | 0.25mL | 1.25mL | 2.5mL |
50mM | 0.05mL | 0.25mL | 0.5mL |