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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NQ 301/5724/50/50 mg
产品编号:5724/50
市  场 价:¥10100.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>蛋白酶类>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$505.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NQ 301/5724/50/50 mg
商品介绍
Description:SelectiveCD45inhibitor
ChemicalName:2-[(4-Acetylphenyl)amino]-3-chloro-1,4-naphthalenedione
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

SelectiveCD45inhibitor(IC50=200nM).Exhibits>200-foldselectivityforCD45oversixrelatedproteintyrosinephosphatases.IncreasesphosphorylationofLckinJurkatcellsandreducesTcellreceptorsignalinginacitvatedsplenocytesinvitro.Blocksinflammationinadelayed-typehypersensitivitymodelinvivo.

TechnicalData

M.Wt325.75
FormulaC18H12ClNO3
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber130089-98-4
PubChemID781109
InChIKeyLSQZKIQSQHZVQS-UHFFFAOYSA-N
SmilesO=C1C(Cl)=C(NC2=CC=C(C(C)=O)C=C2)C(C3=CC=CC=C31)=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO32.58100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight325.75.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.07mL15.35mL30.7mL
5mM0.61mL3.07mL6.14mL
10mM0.31mL1.53mL3.07mL
50mM0.06mL0.31mL0.61mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet