Inhibitorofadenylylcyclase(AC).ExhibitsgreateraffinityforAC5overAC3andAC2(IC50valuesare8.3μM,132μMand1.7mMrespectively).
NKY80isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.
| M.Wt | 229.23 |
| Formula | C12H11N3O2 |
| Storage | Storeat+4°C |
| Purity | ≥98%(HPLC) |
| CASNumber | 299442-43-6 |
| PubChemID | 2772368 |
| InChIKey | SOJUSNIBPPMLCC-UHFFFAOYSA-N |
| Smiles | NC(N=C2)=NC1=C2C(CC(C3=CC=CO3)C1)=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
| Solvent | MaxConc.mg/mL | MaxConc.mM | |
|---|---|---|---|
| Solubility | |||
| DMSO | 22.92 | 100 | |
| ethanol | 2.29 | 10mMwithgentlewarming |
Thefollowingdataisbasedontheproductmolecularweight229.23.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
| Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
|---|---|---|---|
| 1mM | 4.36mL | 21.81mL | 43.62mL |
| 5mM | 0.87mL | 4.36mL | 8.72mL |
| 10mM | 0.44mL | 2.18mL | 4.36mL |
| 50mM | 0.09mL | 0.44mL | 0.87mL |



