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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NK 252/5293/10/10 mg
产品编号:5293/10
市  场 价:¥2580.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$129.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NK 252/5293/10/10 mg
商品介绍
Description:Nrf2activator
ChemicalName:N-[5-(2-Furanyl)-1,3,4-oxADIazol-2-yl]-N'-(2-pyridinylmethyl)urea
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Nrf2activator;interactswiththeNrf2-bindingsiteofKeap1.DownregulatestheexpressionoffibrogenicgenesandincreasesantioxidanteffectsinNASHratmodelsofliverdisease.

CompoundLibraries

NK252isalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt285.26
FormulaC13H11N5O3
StorageStoreat+4°C
Purity≥98%(HPLC)
CASNumber1414963-82-8
PubChemID71618700
InChIKeyFNSCFQXZZNCDAI-UHFFFAOYSA-N
SmilesO=C(NC2=NN=C(C3=CC=CO3)O2)NCC1=CC=CC=N1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
1eq.HCl28.53100
DMSO28.53100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight285.26.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.51mL17.53mL35.06mL
5mM0.7mL3.51mL7.01mL
10mM0.35mL1.75mL3.51mL
50mM0.07mL0.35mL0.7mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet