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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NIBR 189/5203/10/10 mg
产品编号:5203/10
市  场 价:¥3380.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$169.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NIBR 189/5203/10/10 mg
商品介绍
Description:PotentandselectiveEBI2(GPR183)receptorantagoNIST
ChemicalName:(2E)-3-(4-Bromophenyl)-1-[4-4-methoxybenzoyl)-1-piperazinyl]-2-propene-1-one
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

PotentandselectiveEBI2(GPR183)receptorantagonist(IC50valuesare11and15nMforhumanandmouseEBI2receptorsrespectively).ExhibitsselectivityforEBI2overapanelofotherreceptors,enzymesandtransporters.Blocksoxysterol-inducedmigrationofU937monocytecells.Orallybioavailable.

TechnicalData

M.Wt429.31
FormulaC21H21BrN2O3
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber1599432-08-2
PubChemID36295259
InChIKeyOFHXXBRBGWUOHR-NYYWCZLTSA-N
SmilesBrC1=CC=C(/C=C/C(N2CCN(C(C3=CC=C(OC)C=C3)=O)CC2)=O)C=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO42.93100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight429.31.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.33mL11.65mL23.29mL
5mM0.47mL2.33mL4.66mL
10mM0.23mL1.16mL2.33mL
50mM0.05mL0.23mL0.47mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet