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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/NE 100 hydrochloride/3133/10/10 mg
产品编号:3133/10
市  场 价:¥3100.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$155.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/NE 100 hydrochloride/3133/10/10 mg
商品介绍
Description:Selectiveσ1antagoNIST
ChemicalName:4-Methoxy-3-(2-phenylethoxy)-N,N-dipropylbenzeneethanaminehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentandselectiveσ1receptorantagonist(Ki=0.86nM)thatdisplays>55-foldselectivityoverσ2receptorsand>6000-foldselectivityoverD1,D2,5-HT1A,5-HT2andPCPreceptors.ExhibitsreversIBLebinding(Kd=1.2nM)anddisplaysantipsychoticactivityinvivo.Orallyactive.

CompoundLibraries

NE100hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt391.97
FormulaC23H33NO2.HCl
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber149409-57-4
PubChemID9952420
InChIKeyZHGMDXSHODHWHV-UHFFFAOYSA-N
SmilesCCCN(CCC)CCC1=CC=C(OC)C(OCCC2=CC=CC=C2)=C1.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO39.2100
water9.825

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight391.97.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.55mL12.76mL25.51mL
5mM0.51mL2.55mL5.1mL
10mM0.26mL1.28mL2.55mL
50mM0.05mL0.26mL0.51mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet