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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/187-1, N-WASP inhibitor/2067/1/1 mg
产品编号:2067/1
市  场 价:¥4180.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$209.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/187-1, N-WASP inhibitor/2067/1/1 mg
商品介绍
Description:N-WASPinhibitor;inhibitsactinassembly
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

InhibitsneuralWiskott-Aldrichsyndromeprotein(N-WASP)bystABIlizingtheautoinhibitedstateoftheprotein.Blocksphosphatidylinositol4,5-bisphosphate(PIP2)-stimulatedactinassembly(IC50~2μM)butdoesnotdirectlyinhibitactinpolymerization.

TechnicalData

M.Wt1784.13
FormulaC96H122N18O16
SequenceKFPFFPQKFPFFPQ

(Modifications:Phe-2=D-Phe,Pro-3=D-Pro,Phe-4=D-Phe,Pro-6=D-Pro,Cyclized)

StorageDesiccateat-20°C
CASNumber380488-27-7
PubChemID44405676
InChIKeyPHTIQAVQWWOKNF-RNEDXEELSA-N
SmilesNCCCC[C@@H]1NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H]2CCCN2C(=O)[C@@H](CC2=CC=CC=C2)NC1=O

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolubilitySolubleto2mg/mlinwater

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight1784.13.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM0.56mL2.8mL5.6mL
5mM0.11mL0.56mL1.12mL
10mM0.06mL0.28mL0.56mL
50mM0.01mL0.06mL0.11mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet