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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Metyrapone/3292/50/50 mg
产品编号:3292/50
市  场 价:¥1580.00
场      地:美国(厂家直采)
产品分类: 蛋白类>>其它酶>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$79.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Metyrapone/3292/50/50 mg
商品介绍
Description:11-βhydroxylaseinhibitor
ChemicalName:2-Methyl-1,2-di-3-pyridinyl-1-propanone
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

CytochromeP450inhibitor.Blocksglucocorticoidsynthesisviainhibitionofsteroid11-βhydroxylase(CYP11B1)activity(IC50=7.83μM).AlsoinhibitsCYP3A4andcytochromeP450-mediatedω/ω-1hydroxylaseactivity.

CompoundLibraries

MetyraponeisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt226.27
FormulaC14H14N2O
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber54-36-4
PubChemID4174
InChIKeyFJLBFSROUSIWMA-UHFFFAOYSA-N
SmilesO=C(C2=CN=CC=C2)C(C)(C)C1=CC=CN=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO22.63100
ethanol22.63100
water22.63100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight226.27.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.42mL22.1mL44.19mL
5mM0.88mL4.42mL8.84mL
10mM0.44mL2.21mL4.42mL
50mM0.09mL0.44mL0.88mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet