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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Methylprednisolone/4819/50/50 mg
产品编号:4819/50
市  场 价:¥1900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Methylprednisolone/4819/50/50 mg
商品介绍
Description:GlucocorticoidreceptoragoNIST
ChemicalName:11β,17β,21-Trihydroxy-6α-methyl-1,4-pregnADIene-3,20-dione
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Glucocorticoidreceptor(GR)agonist.Displaysanti-inflammatoryandantioxidantproperties.Attenuatesapoptosisinoligodendrocytesafterinjurystimuli.UpregulatesexpressionofBcl-xLviadirectbindingoftheGR/STAT5complex.Neuroprotective.

LicensingInformation

SoldforresearchpurposesunderagreementfromPfizerInc.

CompoundLibraries

MethylprednisoloneisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt374.47
FormulaC22H30O5
StorageStoreat+4°C
Purity≥99%(HPLC)
CASNumber83-43-2
PubChemID6741
InChIKeyVHRSUDSXCMQTMA-PJHHCJLFSA-N
SmilesO=C1C=C[C@@]2(C)C([C@@H](C)C[C@]3([H])[C@@]([H])2[C@@H](O)C[C@@]4(C)[C@]([H])3CC[C@](C(CO)=O)4O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO37.45100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight374.47.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.67mL13.35mL26.7mL
5mM0.53mL2.67mL5.34mL
10mM0.27mL1.34mL2.67mL
50mM0.05mL0.27mL0.53mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet