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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/2-Methoxyestradiol/1807/50/50 mg
产品编号:1807/50
市  场 价:¥8380.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$419.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/2-Methoxyestradiol/1807/50/50 mg
商品介绍
Description:Apoptoticandantiangiogenicagent
ChemicalName:(17β)-2-Methoxyestra-1,3,5(10)-triene-3,17-diol
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Apoptotic,antiproliferativeandantiangiogenicagent,invitroandinvivo;actsviaanestrogenreceptor-independentmechanism.Inducesp53-inducedapoptosisviatwopathways:activationofp38andNF-κB;andactivationofJNKandAP-1leADIngtoBcl-2phosphorylation.Alsoupregulatesdeathreceptor5andbindstotubulin,inhibitingitsassembly.

CompoundLibraries

2-MethoxyestradiolisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt302.41
FormulaC19H26O3
StorageStoreatRT
Purity≥99%(HPLC)
CASNumber362-07-2
PubChemID66414
InChIKeyCQOQDQWUFQDJMK-SSTWWWIQSA-N
SmilesOC1=C(OC)C=C2C(CC[C@]3([H])[C@@]([H])2CC[C@@]4(C)[C@]([H])3CC[C@@H]4O)=C1

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO15.1250

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight302.41.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.31mL16.53mL33.07mL
5mM0.66mL3.31mL6.61mL
10mM0.33mL1.65mL3.31mL
50mM0.07mL0.33mL0.66mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet