Tocris/Meclizine dihydrochloride/4245/50/50 mg,Tocris,,Tocris,Tocris Bioscience,品牌试剂实验Tocris代理 Tocris配体,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Tocris/Meclizine dihydrochloride/4245/50/50 mg

产品编号：4245/50

市场价：¥1900.00

场地：美国(厂家直采)

产品分类：生化试剂>生物分子>受体>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$95.00

品牌： Tocris

公司：Tocris Bioscience

公司分类：

商品介绍

Description:HumanpregnaneXreceptoragoNIST;H₁antagonist

AlternativeNames:Meclozine

ChemicalName:1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazinedihydrochloride

Purity:≥99%(HPLC)

BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HumanpregnaneXreceptor(hPXR)agonist;strongeractivatorofhPXRthanratPXR.IncreaseshPXRtargetgeneexpressioninhumanhepatocyteprimarycultures.AlsoactsasahistamineH₁receptorantagonist.ConfersneuroprotectioninmodelsofpolyQtoxicity.

CompoundLibraries

MeclizinedihydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt	463.87
Formula	C₂₅H₂₇ClN₂.2HCl
Storage	DesiccateatRT
Purity	≥99%(HPLC)
CASNumber	1104-22-9
PubChemID	64713
InChIKey	VCTHNOIYJIXQLV-UHFFFAOYSA-N
Smiles	CC1=CC(CN(CC4)CCN4C(C3=CC=C(Cl)C=C3)C2=CC=CC=C2)=CC=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

	Solvent	MaxConc.mg/mL	MaxConc.mM
Solubility
Solubility	DMSO	23.19	50

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight463.87.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass	1mg	5mg	10mg
1mM	2.16mL	10.78mL	21.56mL
5mM	0.43mL	2.16mL	4.31mL
10mM	0.22mL	1.08mL	2.16mL
50mM	0.04mL	0.22mL	0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet

SafetyDatasheet

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BiologicalActivity

CompoundLibraries

TechnicalData

SolubilityData

PreparingStockSolutions

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