请使用支持JavaScript的浏览器!
主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/Meclizine dihydrochloride/4245/50/50 mg
产品编号:4245/50
市  场 价:¥1900.00
场      地:美国(厂家直采)
产品分类: 生化试剂>生物分子>受体>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$95.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/Meclizine dihydrochloride/4245/50/50 mg
商品介绍
Description:HumanpregnaneXreceptoragoNIST;H1antagonist
AlternativeNames:Meclozine
ChemicalName:1-[(4-Chlorophenyl)phenylmethyl]4-[(3-methylphenyl)methyl]piperazinedihydrochloride
Purity:≥99%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

HumanpregnaneXreceptor(hPXR)agonist;strongeractivatorofhPXRthanratPXR.IncreaseshPXRtargetgeneexpressioninhumanhepatocyteprimarycultures.AlsoactsasahistamineH1receptorantagonist.ConfersneuroprotectioninmodelsofpolyQtoxicity.

CompoundLibraries

MeclizinedihydrochlorideisalsoofferedaspartoftheTocriscreenPlusandTocriscreenLibraryofFDA-ApprovedCompounds.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt463.87
FormulaC25H27ClN2.2HCl
StorageDesiccateatRT
Purity≥99%(HPLC)
CASNumber1104-22-9
PubChemID64713
InChIKeyVCTHNOIYJIXQLV-UHFFFAOYSA-N
SmilesCC1=CC(CN(CC4)CCN4C(C3=CC=C(Cl)C=C3)C2=CC=CC=C2)=CC=C1.Cl.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23.1950

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight463.87.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM2.16mL10.78mL21.56mL
5mM0.43mL2.16mL4.31mL
10mM0.22mL1.08mL2.16mL
50mM0.04mL0.22mL0.43mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet