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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/MS 21570/6298/10/10 mg
产品编号:6298/10
市  场 价:¥2180.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$109.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/MS 21570/6298/10/10 mg
商品介绍
Description:GPR171antagoNIST
ChemicalName:N-Methyl-5-[(phenylmethyl)thio]-1,3,4-thiazADIazol-2-amine
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

GPR171antagonist(IC50=220nM).InhibitsBigLEN(Cat.No.6304)mediatedincreasesin[35S]GTPγSbindinginhypothalamicmembranesandhyperpolarizationofbasolateralamygdalapyramidalneurons.Reducesanxiety-likebehaviorandfearconditioninginmice.

TechnicalData

M.Wt237.34
FormulaC10H11N3S2
StorageStoreat-20°C
Purity≥98%(HPLC)
CASNumber65373-29-7
PubChemID805117
InChIKeyKFLNRVSOQJTXDG-UHFFFAOYSA-N
SmilesCNC1=NN=C(S1)SCC2=CC=CC=C2

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO23.73100
ethanol23.73100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight237.34.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM4.21mL21.07mL42.13mL
5mM0.84mL4.21mL8.43mL
10mM0.42mL2.11mL4.21mL
50mM0.08mL0.42mL0.84mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet