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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
Tocris/MPC 6827 hydrochloride/5231/10/10 mg
产品编号:5231/10
市  场 价:¥3780.00
场      地:美国(厂家直采)
产品分类: 生化试剂>其他>其他试剂>
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$189.00
品      牌: Tocris
公      司:Tocris Bioscience
公司分类:
Tocris/MPC 6827 hydrochloride/5231/10/10 mg
商品介绍
Description:Inhibitorofmicrotubulepolymerization;antimitoticandantitumor
ChemicalName:N-(4-Methoxyphenyl)-N,2-dimethyl-4-quinazolinaminehydrochloride
Purity:≥98%(HPLC)
BIOLOGicalActivityTechnicalDataSolubilityCalculatorsDatasheetsReferences

BiologicalActivity

Potentinhibitorofmicrotubuleformation(IC50=1.5-3.4nM);inhibitspolymerizationoftubulininvitroanddisruptsmicrotubuleformationinseveralcancercelllines.Inhibitstumorgrowthinvitroandinvivo;exhibitspro-apoptoticcharacteristics.Brainpenetrant.

CompoundLibraries

MPC6827hydrochlorideisalsoofferedaspartoftheTocriscreenPlus.FindoutmoreaboutcompoundlibrariesavailablefromTocris.

TechnicalData

M.Wt315.8
FormulaC17H17N3O.HCl
StorageDesiccateatRT
Purity≥98%(HPLC)
CASNumber917369-31-4
PubChemID11638255
InChIKeyVYUWDIKZJLOZJL-UHFFFAOYSA-N
SmilesCC2=NC1=CC=CC=C1C(N(C)C3=CC=C(OC)C=C3)=N2.Cl

Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.

AllTocrisproductsareintendedforlaboratoryresearchuseonly.

SolubilityData

SolventMaxConc.mg/mLMaxConc.mM
Solubility
DMSO31.58100
water31.58100

PreparingStockSolutions

Thefollowingdataisbasedontheproductmolecularweight315.8.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.

Concentration/SolventVolume/Mass1mg5mg10mg
1mM3.17mL15.83mL31.67mL
5mM0.63mL3.17mL6.33mL
10mM0.32mL1.58mL3.17mL
50mM0.06mL0.32mL0.63mL

ProductDatasheets

CertificateofAnalysis/ProductDatasheet
SafetyDatasheet