Novel,non-toxicimmunosuppressiveagent.Inhibitshumanmixedlymphocytereactioninvitro(ED50=2.7μM)andprolongsskingraftsurvivalinmice.Producesa98.1%reductioninantibodyresponsefollowingoraladmiNISTrationinrabbits.
M.Wt | 240.24 |
Formula | C7H8N6O2S |
Storage | Storeat+4°C |
Purity | ≥99%(HPLC) |
CASNumber | 177653-76-8 |
PubChemID | 364622 |
InChIKey | NMBDIMPYACLUDE-UHFFFAOYSA-N |
Smiles | CN1C=NN=C1SC1=C(N=CN1C)[N+]([O-])=O |
Thetechnicaldataprovidedaboveisforguidanceonly.ForbatchspecificdatarefertotheCertificateofAnalysis.
AllTocrisproductsareintendedforlaboratoryresearchuseonly.
Solvent | MaxConc.mg/mL | MaxConc.mM | |
---|---|---|---|
Solubility | |||
DMSO | 4.8 | 20 | |
water | 2.4 | 10 |
Thefollowingdataisbasedontheproductmolecularweight240.24.Batchspecificmolecularweightsmayvaryfrombatchtobatchduetosolventofhydration,whichwillaffectthesolventvolumesrequiredtopreparestocksolutions.
Concentration/SolventVolume/Mass | 1mg | 5mg | 10mg |
---|---|---|---|
1mM | 4.16mL | 20.81mL | 41.63mL |
5mM | 0.83mL | 4.16mL | 8.33mL |
10mM | 0.42mL | 2.08mL | 4.16mL |
50mM | 0.08mL | 0.42mL | 0.83mL |